Amalia TROUSSON
Maitre de Conférences
TROUSSON
Amalia
Maitre de Conférences
MCF
Resume
Since 2010 Associate professor in physiology. Université Clermont Auvergne
2009-2010 Postodoctoral fellow, Max Planck Institute for experimental medicine, Neurogentics department ,Göttingen, Germany
Dr M.Sereda's Team
"Role of Wnt/β-catenin signaling in the myelination of central and peripheric nervous system"
"Therapeutic effects of LXR ligands in a rat model of Charcot-Marie-Tooth disease"
2004-2008 Ph.D, CNRS UPR2228 laboratory of Dr Philippe Djian and INSERM U788, laboratory of Dr Michael Schumacher.
Pr C. Massaad's team
"Involvment of steroids and Wnt signalling in glial cells : implication in myelination and inflammation"
Publications
Cholesterol Dietary Intake and Tumor Cell Homeostasis Drive Early Epithelial Tumorigenesis: A Potential Modelization of Early Prostate Tumorigenesis.
Published on 06 Jun 2024 in Cancers , vol. 16
Vialat M , Baabdaty E , Trousson A , Kocer A , Lobaccaro JA, Baron S , Morel L , de Joussineau C
Liver X Receptors Enhance Epithelial to Mesenchymal Transition in Metastatic Prostate Cancer Cells.
Published on 06 Aug 2024 in Cancers , vol. 16
Bouchareb E , Dallel S , De Haze A , Damon-Soubeyrand C , Renaud Y , Baabdaty E , Vialat M , Fabre J , Pouchin P , De Joussineau C , Degoul F , Sanmukh S, Gendronneau J , Sanchez P, Gonthier-Gueret C, Trousson A , Morel L , Lobaccaro JM , Kocer A , Baron S
Persistent organic pollutants promote aggressiveness in prostate cancer.
Published on 01 Sep 2023 in Oncogene , vol. 42 - pp 2854-2867
Buñay J, Kossai M, Damon-Soubeyrant C, De Haze A , Saru JP , Trousson A , de Joussineau C , Bouchareb E , Kocer A , Vialat M , Dallel S , Degoul F , Bost F, Clavel S, Penault-Llorca F, Valli MP, Guy L, Matthews J, Renaud Y , Ittmann M, Jones J, Morel L , Lobaccaro JM , Baron S
Screening for liver X receptor modulators: Where are we and for what use?
Published on 01 Aug 2021 in British journal of pharmacology , vol. 178 - pp 3277-3293
Buñay J, Fouache A , Trousson A , de Joussineau C , Bouchareb E , Zhu Z , Kocer A , Morel L , Baron S , Lobaccaro JA
Absence of nuclear receptors LXRs impairs immune response to androgen deprivation and leads to prostate neoplasia.
Published on 07 Dec 2020 in PLoS biology , vol. 18 - pp e3000948
Bousset L , Septier A , Bunay J, Voisin A , Guiton R , Damon-Soubeyrant C, Renaud Y , De Haze A , Sapin V , Fogli A , Rambur A , De Joussineau C , Kocer A , Trousson A , Henry-Berger J , Höring M, Liebisch G, Matysik S, Lobaccaro JA, Morel L , Baron S
Sequential Ras/MAPK and PI3K/AKT/mTOR pathways recruitment drives basal extrusion in the prostate-like gland of Drosophila.
Published on 08 May 2020 in Nature communications , vol. 11 - pp 2300
Rambur A , Lours-Calet C, Beaudoin C , Buñay J, Vialat M , Mirouse V , Trousson A , Renaud Y , Lobaccaro JA, Baron S , Morel L , de Joussineau C
Ethanolic extract of Algerian propolis decreases androgen receptor transcriptional activity in cultured LNCaP cells.
Published on 01 May 2019 in The Journal of steroid biochemistry and molecular biology , vol. 189 - pp 108-115
Zabaiou N , Fouache A , Trousson A , Buñay-Noboa J, Marceau G , Sapin V , Zellagui A, Baron S , Lahouel M , Lobaccaro JA
Flavonoids differentially modulate liver X receptors activity-Structure-function relationship analysis.
Published on 01 Jun 2019 in The Journal of steroid biochemistry and molecular biology , vol. 190 - pp 173-182
Fouache A , Zabaiou N , De Joussineau C , Morel L , Silvente-Poirot S, Namsi A, Lizard G, Poirot M, Makishima M, Baron S , Lobaccaro JA, Trousson A
Individual Comparison of Cholesterol Metabolism in Normal and Tumour Areas in Radical Prostatectomy Specimens from Patients with Prostate Cancer: Results of the CHOMECAP Study.
Published on 30 Mar 2019 in European urology oncology , vol. 2 - pp 198-206
Celhay O , Bousset L , Guy L, Kemeny JL, Leoni V, Caccia C, Trousson A , Damon-Soubeyrant C, De Haze A , Sabourin L, Godfraind C, de Joussineau C , Pereira B, Morel L , Lobaccaro JM , Baron S
New Insights in Prostate Cancer Development and Tumor Therapy: Modulation of Nuclear Receptors and the Specific Role of Liver X Receptors.
Published on 28 Aug 2018 in International journal of molecular sciences , vol. 19
Bousset L , Rambur A , Fouache A , Bunay J, Morel L , Lobaccaro JA, Baron S , Trousson A , de Joussineau C
Biological properties of propolis extracts: Something new from an ancient product.
Published on 30 Oct 2017 in Chemistry and physics of lipids , vol. 207 - pp 214-222
Zabaiou N , Fouache A , Trousson A , Baron S , Zellagui A, Lahouel M , Lobaccaro JA
Role of the liver X receptors in skin physiology: Putative pharmacological targets in human diseases.
Published on 30 Oct 2017 in Chemistry and physics of lipids , vol. 207 - pp 59-68
Ouedraogo ZG, Fouache A , Trousson A , Baron S , Lobaccaro JA
Liver X Receptors (LXRs) Alpha and Beta Play Distinct Roles in the Mouse Epididymis.
Published on 01 Mar 2016 in Biology of reproduction , vol. 94 - pp 55
Whitfield M , Ouvrier A, Cadet R , Damon-Soubeyrand C , Guiton R , Janny L , Kocer A , Marceau G , Pons-Rejraji H , Trousson A , Drevet JR , Saez F
Lipid Homeostasis and Ligands for Liver X Receptors: Identification and Characterization.
Published on 01 Jan 2016 in Methods in molecular biology (Clifton, N.J.) , vol. 1443 - pp 13-9
Lobaccaro JM , Beaudoin C , Bayala B , Baron S , Trousson A
Once and for all, LXRα and LXRβ are gatekeepers of the endocrine system.
Published on 30 Jun 2016 in Molecular aspects of medicine , vol. 49 - pp 31-46
Maqdasy S , Trousson A , Tauveron I , Volle DH , Baron S , Lobaccaro JM
Identification of the Functions of Liver X Receptor-β in Sertoli Cells Using a Targeted Expression-Rescue Model.
Published on 30 Dec 2015 in Endocrinology , vol. 156 - pp 4545-57
Maqdasy S , El Hajjaji FZ, Baptissart M , Viennois E, Oumeddour A , Brugnon F , Trousson A , Tauveron I , Volle D, Lobaccaro JM , Baron S
Enolase is regulated by Liver X Receptors.
Published on 30 Jul 2015 in Steroids , vol. 99 - pp 266-71
De Boussac H , Maqdasy S , Trousson A , Zelcer N, Volle DH , Lobaccaro JM , Baron S
Liver X receptor activation promotes polyunsaturated fatty acid synthesis in macrophages: relevance in the context of atherosclerosis.
Published on 30 Jun 2015 in Arteriosclerosis, thrombosis, and vascular biology , vol. 35 - pp 1357-65
Varin A, Thomas C, Ishibashi M, Ménégaut L, Gautier T, Trousson A , Bergas V, de Barros JP, Narce M, Lobaccaro JM , Lagrost L, Masson D
Comparaison appariée des flux du cholestérol cellulaire dans les tissus sains et cancéreux prostatiques : résultats de l’étude Chomecap.
Published on 30 Nov 2015 in Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie , vol. 25 - pp 727-8
Celhay O , Laurent G, Alioui A , Trousson A , Kemeny L, Pereira B, Leoni V, Lobaccaro J, Baron S
Environmental estrogen exposure during fetal life: a time bomb for prostate cancer.
Published on 30 Mar 2014 in Endocrinology , vol. 155 - pp 656-8
Lipids, LXRs and prostate cancer: are HDACs a new link?
Published on 01 Jul 2013 in Biochemical pharmacology , vol. 86 - pp 168-74
Hoang JJ, Baron S , Volle DH , Lobaccaro JM , Trousson A
Oxysterol receptors and their therapeutic applications in cancer conditions.
Published on 30 Sep 2013 in Expert opinion on therapeutic targets , vol. 17 - pp 1029-38
De Boussac H , Alioui A , Viennois E, Dufour J , Trousson A , Vega A , Guy L, Volle DH , Lobaccaro JM , Baron S
Liver x receptors protect from development of prostatic intra-epithelial neoplasia in mice.
Published on 30 May 2013 in PLoS genetics , vol. 9 - pp e1003483
Pommier AJ, Dufour J , Alves G, Viennois E, De Boussac H , Trousson A , Volle DH , Caira F , Val P , Arnaud P , Lobaccaro JM , Baron S
LXR, prostate cancer and cholesterol: the Good, the Bad and the Ugly.
Published on 01 Mar 2013 in American journal of cancer research , vol. 3 - pp 58-69
de Boussac H , Pommier AJ, Dufour J , Trousson A , Caira F , Volle DH , Baron S , Lobaccaro JM
Wnt/beta-catenin signaling is an essential and direct driver of myelin gene expression and myelinogenesis.
Published on 09 Mar 2011 in The Journal of neuroscience : the official journal of the Society for Neuroscience , vol. 31 - pp 3729-42
Tawk M, Makoukji J, Belle M, Fonte C, Trousson A , Hawkins T, Li H, Ghandour S, Schumacher M, Massaad C
25-hydroxycholesterol provokes oligodendrocyte cell line apoptosis and stimulates the secreted phospholipase A2 type IIA via LXR beta and PXR.
Published on 30 May 2009 in Journal of neurochemistry , vol. 109 - pp 945-58
Trousson A , Bernard S, Petit PX, Liere P, Pianos A, El Hadri K, Lobaccaro JM , Ghandour MS, Raymondjean M, Schumacher M, Massaad C
