Antoine MARTINEZ
Chef d'équipe
MARTINEZ
Antoine
Chef d'équipe
DR
Publications
Sex differences in adrenal cortex beta-catenin immunolocalisation of the Saharan gerbil, Libyan jird (Meriones libycus, Lichtenstein, 1823).
Published on 01 Jan 2023 in Folia morphologica , vol. 82 - pp 830-840
Aknoun-Sail N, Zatra Y, Sahut-Barnola I , Benmouloud A, Kheddache A, Khaldoun M, Charallah S, Khammar F, Martinez A , Amirat Z
Gene expression changes in the brain of a Cushing’s syndrome mouse model.
Published on 01 Apr 2022 in Journal of neuroendocrinology , vol. 34 - pp e13125
Amaya JM, Viho EMG, Sips HCM, Lalai RA, Sahut-Barnola I , Dumontet T , Montanier N , Pereira AM, Martinez A , Meijer OC
Mislocalization of protein kinase A drives pathology in Cushing’s syndrome.
Published on 12 Jul 2022 in Cell reports , vol. 40 - pp 111073
Omar MH, Byrne DP, Jones KN, Lakey TM, Collins KB, Lee KS, Daly LA, Forbush KA, Lau HT, Golkowski M, McKnight GS, Breault DT, Lefrançois-Martinez AM , Martinez A , Eyers CE, Baird GS, Ong SE, Smith FD, Eyers PA, Scott JD
Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation in mice.
Published on 21 Dec 2022 in Nature communications , vol. 13 - pp 7858
Dufour D , Dumontet T , Sahut-Barnola I, Carusi A, Onzon M , Pussard E, Wilmouth JJ , Olabe J , Lucas C , Levasseur A , Damon-Soubeyrand C , Pointud JC , Roucher-Boulez F , Tauveron I , Bossis G, Yeh ET, Breault DT, Val P , Lefrançois-Martinez AM, Martinez A
Effects of Long-Term Endogenous Corticosteroid Exposure on Brain Volume and Glial Cells in the AdKO Mouse.
Published on 10 Feb 2021 in Frontiers in neuroscience , vol. 15 - pp 604103
Amaya JM, Suidgeest E, Sahut-Barnola I , Dumontet T , Montanier N , Pagès G, Keller C, van der Weerd L, Pereira AM, Martinez A , Meijer OC
HIF1α is a direct regulator of steroidogenesis in the adrenal gland.
Published on 01 Apr 2021 in Cellular and molecular life sciences : CMLS , vol. 78 - pp 3577-3590
Watts D, Stein J, Meneses A, Bechmann N, Neuwirth A, Kaden D, Krüger A, Sinha A, Alexaki VI, Luis Gustavo Perez-Rivas, Kircher S, Martinez A , Theodoropoulou M, Eisenhofer G, Peitzsch M, El-Armouche A, Chavakis T, Wielockx B
Co-culture of monocytes and zona fasciculata adrenal cells: An in vitro model to study the immune-adrenal cross-talk.
Published on 15 Apr 2021 in Molecular and cellular endocrinology , vol. 526 - pp 111195
Fudulu DP, Horn G, Hazell G, Lefrançois-Martinez AM , Martinez A , Angelini GD, Lightman SL, Spiga F
Adrenal androgens, adrenarche, and zona reticularis: A human affair?
Published on 15 May 2021 in Molecular and cellular endocrinology , vol. 528 - pp 111239
Adrenal androgens, adrenarche, and zona reticularis: A human affair?
Published on 15 May 2021 in Molecular and cellular endocrinology , vol. 528 - pp 111239
Involvement of CREB-regulated transcription coactivators (CRTC) in transcriptional activation of steroidogenic acute regulatory protein (Star) by ACTH.
Published on 01 Jan 2020 in Molecular and cellular endocrinology , vol. 499 - pp 110612
Smith LIF, Huang V, Olah M, Trinh L, Liu Y, Hazell G, Conway-Campbell B, Zhao Z, Martinez A , Lefrançois-Martinez AM , Lightman S, Spiga F, Aguilera G
EZH2 cooperates with E2F1 to stimulate expression of genes involved in adrenocortical carcinoma aggressiveness.
Published on 30 Aug 2019 in British journal of cancer , vol. 121 - pp 384-394
Tabbal H , Septier A , Mathieu M , Drelon C , Rodriguez S , Djari C , Batisse-Lignier M , Tauveron I , Pointud JC , Sahut-Barnola I , Ragazzon B, Assié G, Bertherat J, Lefrançois-Martinez AM , Martinez A , Val P
Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex.
Published on 26 Dec 2018 in Proceedings of the National Academy of Sciences of the United States of America , vol. 115 - pp E12265-E12274
Mathieu M , Drelon C , Rodriguez S , Tabbal H , Septier A , Damon-Soubeyrand C , Dumontet T , Berthon A , Sahut-Barnola I , Djari C , Batisse-Lignier M , Pointud JC , Richard D, Kerdivel G, Calméjane MA, Boeva V, Tauveron I , Lefrançois-Martinez AM , Martinez A , Val P
P53/Rb inhibition induces metastatic adrenocortical carcinomas in a preclinical transgenic model.
Published on 30 Aug 2017 in Oncogene , vol. 36 - pp 4445-4456
Batisse-Lignier M , Sahut-Barnola I , Tissier F, Dumontet T , Mathieu M , Drelon C , Pointud JC , Damon-Soubeyrand C , Marceau G , Kemeny JL, Bertherat J, Tauveron I , Val P , Martinez A , Lefrançois-Martinez AM
Mouse Models Recapitulating Human Adrenocortical Tumors: What Is Lacking?
Published on 15 Jul 2016 in Frontiers in endocrinology , vol. 7 - pp 93
Leccia F , Batisse-Lignier M , Sahut-Barnola I , Val P , Lefrançois-Martinez AM , Martinez A
PKA regulatory subunit 1A inactivating mutation induces serotonin signaling in primary pigmented nodular adrenal disease.
Published on 22 Sep 2016 in JCI insight , vol. 1 - pp e87958
Bram Z, Louiset E, Ragazzon B, Renouf S, Wils J, Duparc C, Boutelet I, Rizk-Rabin M, Libé R, Young J, Carson D, Vantyghem MC, Szarek E, Martinez A , Stratakis CA, Bertherat J, Lefebvre H
Editorial: Adrenal Cortex: From Physiology to Disease.
Published on 01 Jun 2016 in Frontiers in endocrinology , vol. 7 - pp 51
The adrenal capsule is a signaling center controlling cell renewal and zonation through Rspo3.
Published on 15 Jun 2016 in Genes & development , vol. 30 - pp 1389-94
Vidal V, Sacco S, Rocha AS, da Silva F, Panzolini C, Dumontet T , Doan TM, Shan J, Rak-Raszewska A, Bird T, Vainio S, Martinez A , Schedl A
WNT/β-catenin signalling is activated in aldosterone-producing adenomas and controls aldosterone production.
Published on 15 Feb 2014 in Human molecular genetics , vol. 23 - pp 889-905
Berthon A , Drelon C , Ragazzon B, Boulkroun S, Tissier F, Amar L, Samson-Couterie B, Zennaro MC, Plouin PF, Skah S, Plateroti M, Lefèbvre H, Sahut-Barnola I , Batisse-Lignier M , Assié G, Lefrançois-Martinez AM , Bertherat J, Martinez A , Val P
Hypothalamo-pituitary and immune-dependent adrenal regulation during systemic inflammation.
Published on 03 Sep 2013 in Proceedings of the National Academy of Sciences of the United States of America , vol. 110 - pp 14801-6
Kanczkowski W, Alexaki VI, Tran N, Großklaus S, Zacharowski K, Martinez A , Popovics P, Block NL, Chavakis T, Schally AV, Bornstein SR
WT1 maintains adrenal-gonadal primordium identity and marks a population of AGP-like progenitors within the adrenal gland.
Published on 14 Oct 2013 in Developmental cell , vol. 27 - pp 5-18
Bandiera R, Vidal VP, Motamedi FJ, Clarkson M, Sahut-Barnola I , von Gise A, Pu WT, Hohenstein P, Martinez A , Schedl A
Aldo-Keto Reductases 1B in Endocrinology and Metabolism.
Published on 02 Aug 2012 in Frontiers in pharmacology , vol. 3 - pp 148
Pastel E , Pointud JC , Volat F, Martinez A , Lefrançois-Martinez AM
The cAMP pathway and the control of adrenocortical development and growth.
Published on 31 Mar 2012 in Molecular and cellular endocrinology , vol. 351 - pp 28-36
de Joussineau C , Sahut-Barnola I , Levy I, Saloustros E, Val P , Stratakis CA, Martinez A
Analysis of the role of Igf2 in adrenal tumour development in transgenic mouse models.
Published on 28 Aug 2012 in PloS one , vol. 7 - pp e44171
Drelon C , Berthon A , Ragazzon B, Tissier F, Bandiera R, Sahut-Barnola I, de Joussineau C , Batisse-Lignier M , Lefrançois-Martinez AM, Bertherat J, Martinez A , Val P
Wnt/β-catenin signalling in adrenal physiology and tumour development.
Published on 31 Mar 2012 in Molecular and cellular endocrinology , vol. 351 - pp 87-95
Berthon A , Martinez A , Bertherat J, Val P
Depressed levels of prostaglandin F2α in mice lacking Akr1b7 increase basal adiposity and predispose to diet-induced obesity.
Published on 30 Nov 2012 in Diabetes , vol. 61 - pp 2796-806
Volat FE, Pointud JC , Pastel E , Morio B, Sion B, Hamard G, Guichardant M, Colas R, Lefrançois-Martinez AM , Martinez A
Transcriptional control of adrenal steroidogenesis: novel connection between Janus kinase (JAK) 2 protein and protein kinase A (PKA) through stabilization of cAMP response element-binding protein (CREB) transcription factor.
Published on 23 Sep 2011 in The Journal of biological chemistry , vol. 286 - pp 32976-85
Lefrancois-Martinez AM , Blondet-Trichard A, Binart N, Val P , Chambon C, Sahut-Barnola I , Pointud JC , Martinez A
Identification, cloning and regulation of cDNA encoding aldo-keto reductase 1B7 in the adrenal gland of two Saharan rodents Meriones libycus (Libyan jird) and Gerbillus gerbillus (gerbil).
Published on 01 Dec 2011 in General and comparative endocrinology , vol. 174 - pp 292-300
Mataoui-Mazari H, Amirat Z, Khammar F, Martinez A
Cushing’s syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout mice.
Published on 10 Jun 2010 in PLoS genetics , vol. 6 - pp e1000980
Sahut-Barnola I , de Joussineau C , Val P , Lambert-Langlais S, Damon C, Lefrançois-Martinez AM, Pointud JC , Marceau G , Sapin V , Tissier F, Ragazzon B, Bertherat J, Kirschner LS, Stratakis CA, Martinez A
Constitutive beta-catenin activation induces adrenal hyperplasia and promotes adrenal cancer development.
Published on 15 Apr 2010 in Human molecular genetics , vol. 19 - pp 1561-76
Berthon A , Sahut-Barnola I , Lambert-Langlais S, de Joussineau C , Damon-Soubeyrand C , Louiset E, Taketo MM, Tissier F, Bertherat J, Lefrançois-Martinez AM, Martinez A , Val P
Aldo keto reductase 1B7 and prostaglandin F2alpha are regulators of adrenal endocrine functions.
Published on 07 Oct 2009 in PloS one , vol. 4 - pp e7309
Lambert-Langlais S, Pointud JC , Lefrançois-Martinez AM , Volat F, Manin M, Coudoré F, Val P , Sahut-Barnola I , Ragazzon B, Louiset E, Delarue C, Lefebvre H, Urade Y, Martinez A
A transgenic mouse line with specific Cre recombinase expression in the adrenal cortex.
Published on 05 Mar 2009 in Molecular and cellular endocrinology , vol. 300 - pp 197-204
Lambert-Langlais S, Val P , Guyot S, Ragazzon B, Sahut-Barnola I , De Haze A , Lefrançois-Martinez AM , Martinez A
Prostaglandin F2alpha synthase activities of aldo-keto reductase 1B1, 1B3 and 1B7.
Published on 02 Mar 2009 in Journal of biochemistry , vol. 145 - pp 161-8
Kabututu Z, Manin M, Pointud JC , Maruyama T, Nagata N, Lambert S , Lefrançois-Martinez AM, Martinez A , Urade Y
24-dehydrocholesterol reductase/seladin-1: a key protein differentially involved in adrenocorticotropin effects observed in human and rat adrenal cortex.
Published on 30 Sep 2009 in Endocrinology , vol. 150 - pp 4180-90
Battista MC, Roberge C, Martinez A , Gallo-Payet N
Inactivation of the Carney complex gene 1 (protein kinase A regulatory subunit 1A) inhibits SMAD3 expression and TGF beta-stimulated apoptosis in adrenocortical cells.
Published on 15 Sep 2009 in Cancer research , vol. 69 - pp 7278-84
Ragazzon B, Cazabat L, Rizk-Rabin M, Assie G, Groussin L, Fierrard H, Perlemoine K, Martinez A , Bertherat J
Mouse model for bilateral adrenal hyperplasia.
Published on 30 Jun 2009 in Annales d'endocrinologie , vol. 70 - pp 194
Sahut-Barnola I , De Joussineau C , Val P , Lambert-Langlais S, Lefrançois-Martinez AM , Pointud JC , Marceau G , Sapin V , Ragazzon B, Bertherat J, Kirschner LS, Stratakis CA, Martinez A
