Helene HOLOTA
Ingénieur d'étude
HOLOTA
Helene
Ingénieur d'étude
IR
Publications
Alternative splicing is an FXRα loss-of-function mechanism and impacts energy metabolism in hepatocarcinoma cells.
Published on 26 Nov 2024 in The Journal of biological chemistry - pp 108022
Garcia M , Holota H , De Haze A , Saru JP , Sanchez P , Battistelli E , Thirouard L , Monrose M , Benoit G, Volle DH, Beaudoin C
Constitutive Androstane Receptor Regulates Germ Cell Homeostasis, Sperm Quality, and Male Fertility via Akt-Foxo1 Pathway.
Published on 24 Sep 2024 in Advanced science (Weinheim, Baden-Wurttemberg, Germany) - pp e2402082
Monrose M , Holota H , Martinez G, Damon-Soubeyrand C , Thirouard L , Martinot E , Battistelli E , de Haze A , Bravard S , Tamisier C , Caira F , Coutton C, Barbotin AL, Boursier A, Lakhal L, Beaudoin C , Volle DH
Understanding the role of endocrine disrupting chemicals in testicular germ cell cancer: Insights into molecular mechanisms.
Published on 29 Aug 2024 in Molecular aspects of medicine , vol. 99 - pp 101307
Pang WK , Kuznetsova E , Holota H , De Haze A , Beaudoin C , Volle DH
Metallome deregulation and health-related impacts due to long-term exposure to recent volcanic ash deposits: New chemical and isotopic insights.
Published on 10 Jul 2022 in The Science of the total environment , vol. 829 - pp 154383
Sauzéat L , Eychenne J , Gurioli L, Boyet M, Jessop DE, Moretti R, Monrose M , Holota H , Beaudoin C , Volle DH
Intestinal microbiota defines the GUT-TESTIS axis.
Published on 30 Apr 2022 in Gut , vol. 71 - pp 844-845
Martinot E , Thirouard L , Holota H , Monrose M , Garcia M , Beaudoin C , Volle DH
Identification of a Crosstalk among TGR5, GLIS2, and TP53 Signaling Pathways in the Control of Undifferentiated Germ Cell Homeostasis and Chemoresistance.
Published on 30 Jun 2022 in Advanced science (Weinheim, Baden-Wurttemberg, Germany) , vol. 9 - pp e2200626
Thirouard L , Holota H , Monrose M , Garcia M , de Haze A , Damon-Soubeyrand C, Renaud Y , Saru JP , Perino A, Schoonjans K, Beaudoin C , Volle DH
Identification of the Role of TGR5 in the Regulation of Leydig Cell Homeostasis.
Published on 06 Dec 2022 in International journal of molecular sciences , vol. 23
Holota H , De Haze A , Martinot E , Monrose M , Saru JP , Caira F , Beaudoin C , Volle DH
Metallome deregulation and health-related impacts due to long-term exposure to recent volcanic ash deposits: New chemical and isotopic insights.
Published on 10 Jul 2022 in The Science of the total environment , vol. 829 - pp 154383
Sauzéat L , Eychenne J , Gurioli L, Boyet M, Jessop DE, Moretti R, Monrose M , Holota H , Beaudoin C , Volle DH
Analysis of the Reversible Impact of the Chemodrug Busulfan on Mouse Testes.
Published on 13 Sep 2021 in Cells , vol. 10
Thirouard L , Holota H , Monrose M , Garcia M , De Haze A , Saru JP , Caira F , Beaudoin C , Volle DH
New perspectives on PPAR, VDR and FXRα as new actors in testicular pathophysiology.
Published on 30 Apr 2021 in Molecular aspects of medicine , vol. 78 - pp 100886
Monrose M , Thirouard L , Garcia M , Holota H , De Haze A , Caira F , Beaudoin C , Volle DH
Nuclear receptors in physiology and pathophysiology.
Published on 30 Apr 2021 in Molecular aspects of medicine , vol. 78 - pp 100956
Farnesoid X receptor alpha (FXRα) is a critical actor of the development and pathologies of the male reproductive system.
Published on 30 Dec 2019 in Cellular and molecular life sciences : CMLS , vol. 76 - pp 4849-4859
Garcia M , Thirouard L , Monrose M , Holota H , De Haze A , Caira F , Beaudoin C , Volle DH
Fxralpha gene is a target gene of hCG signaling pathway and represses hCG induced steroidogenesis.
Published on 30 Nov 2019 in The Journal of steroid biochemistry and molecular biology , vol. 194 - pp 105460
Holota H , Thirouard L , Garcia M , Monrose M , de Haze A , Saru JP , Caira F , Beaudoin C , Volle DH
Crosstalk between BPA and FXRα Signaling Pathways Lead to Alterations of Undifferentiated Germ Cell Homeostasis and Male Fertility Disorders.
Published on 09 Oct 2018 in Stem cell reports , vol. 11 - pp 944-958
Sèdes L , Desdoits-Lethimonier C, Rouaisnel B , Holota H , Thirouard L , Lesne L, Damon-Soubeyrand C, Martinot E , Saru JP , Mazaud-Guittot S, Caira F , Beaudoin C , Jégou B, Volle DH
Multigenerational impacts of bile exposure are mediated by TGR5 signaling pathways.
Published on 15 Nov 2018 in Scientific reports , vol. 8 - pp 16875
Baptissart M , Sèdes L , Holota H , Thirouard L , Martinot E , de Haze A , Rouaisnel B , Caira F , Beaudoin C , Volle DH
Nuclear Receptor Metabolism of Bile Acids and Xenobiotics: A Coordinated Detoxification System with Impact on Health and Diseases.
Published on 17 Nov 2018 in International journal of molecular sciences , vol. 19
Garcia M , Thirouard L , Sedès L , Monrose M , Holota H , Caira F , Volle DH , Beaudoin C
The Bile Acid Nuclear Receptor FXRα Is a Critical Regulator of Mouse Germ Cell Fate.
Published on 11 Jul 2017 in Stem cell reports , vol. 9 - pp 315-328
Martinot E , Sèdes L , Baptissart M , Holota H , Rouaisnel B , Damon-Soubeyrand C , De Haze A , Saru JP , Thibault-Carpentier C, Keime C, Lobaccaro JA, Baron S , Benoit G, Caira F , Beaudoin C , Volle DH
The Bile Acid Nuclear Receptor FXRα Is a Critical Regulator of Mouse Germ Cell Fate.
Published on 11 Jul 2017 in Stem cell reports , vol. 9 - pp 315-328
Martinot E , Sèdes L , Baptissart M , Holota H , Rouaisnel B , Damon-Soubeyrand C, De Haze A , Saru JP , Thibault-Carpentier C, Keime C, Lobaccaro JA, Baron S , Benoit G, Caira F , Beaudoin C , Volle DH
