Laurent MOREL
Professeur des Universités
MOREL
Laurent
Professeur des Universités
PU
Publications
Cholesterol Dietary Intake and Tumor Cell Homeostasis Drive Early Epithelial Tumorigenesis: A Potential Modelization of Early Prostate Tumorigenesis.
Published on 06 Jun 2024 in Cancers , vol. 16
Vialat M , Baabdaty E , Trousson A , Kocer A , Lobaccaro JA, Baron S , Morel L , de Joussineau C
Liver X Receptors Enhance Epithelial to Mesenchymal Transition in Metastatic Prostate Cancer Cells.
Published on 06 Aug 2024 in Cancers , vol. 16
Bouchareb E , Dallel S , De Haze A , Damon-Soubeyrand C , Renaud Y , Baabdaty E , Vialat M , Fabre J , Pouchin P , De Joussineau C , Degoul F , Sanmukh S, Gendronneau J , Sanchez P, Gonthier-Gueret C, Trousson A , Morel L , Lobaccaro JM , Kocer A , Baron S
Persistent organic pollutants promote aggressiveness in prostate cancer.
Published on 01 Sep 2023 in Oncogene , vol. 42 - pp 2854-2867
Buñay J, Kossai M, Damon-Soubeyrant C, De Haze A , Saru JP , Trousson A , de Joussineau C , Bouchareb E , Kocer A , Vialat M , Dallel S , Degoul F , Bost F, Clavel S, Penault-Llorca F, Valli MP, Guy L, Matthews J, Renaud Y , Ittmann M, Jones J, Morel L , Lobaccaro JM , Baron S
Screening for liver X receptor modulators: Where are we and for what use?
Published on 01 Aug 2021 in British journal of pharmacology , vol. 178 - pp 3277-3293
Buñay J, Fouache A , Trousson A , de Joussineau C , Bouchareb E , Zhu Z , Kocer A , Morel L , Baron S , Lobaccaro JA
MEN1 silencing aggravates tumorigenic potential of AR-independent prostate cancer cells through nuclear translocation and activation of JunD and β-catenin.
Published on 26 Aug 2021 in Journal of experimental & clinical cancer research : CR , vol. 40 - pp 270
Luo Y, Vlaeminck-Guillem V, Baron S , Dallel S , Zhang CX, Le Romancer M
Drosophila Accessory Gland: A Complementary In Vivo Model to Bring New Insight to Prostate Cancer.
Published on 10 Sep 2021 in Cells , vol. 10
Rambur A , Vialat M , Beaudoin C , Lours-Calet C, Lobaccaro JM , Baron S , Morel L , de Joussineau C
Absence of nuclear receptors LXRs impairs immune response to androgen deprivation and leads to prostate neoplasia.
Published on 07 Dec 2020 in PLoS biology , vol. 18 - pp e3000948
Bousset L , Septier A , Bunay J, Voisin A , Guiton R , Damon-Soubeyrant C, Renaud Y , De Haze A , Sapin V , Fogli A , Rambur A , De Joussineau C , Kocer A , Trousson A , Henry-Berger J , Höring M, Liebisch G, Matysik S, Lobaccaro JA, Morel L , Baron S
Multiple functions of the scaffold protein Discs large 5 in the control of growth, cell polarity and cell adhesion in Drosophila melanogaster.
Published on 18 Jun 2020 in BMC developmental biology , vol. 20 - pp 10
Venugopal P , Veyssière H , Couderc JL , Richard G , Vachias C , Mirouse V
Oriented basement membrane fibrils provide a memory for F-actin planar polarization via the Dystrophin-Dystroglycan complex during tissue elongation.
Published on 08 Apr 2020 in Development (Cambridge, England) , vol. 147
Cerqueira Campos F , Dennis C , Alégot H , Fritsch C , Isabella A, Pouchin P , Bardot O , Horne-Badovinac S, Mirouse V
Sequential Ras/MAPK and PI3K/AKT/mTOR pathways recruitment drives basal extrusion in the prostate-like gland of Drosophila.
Published on 08 May 2020 in Nature communications , vol. 11 - pp 2300
Rambur A , Lours-Calet C, Beaudoin C , Buñay J, Vialat M , Mirouse V , Trousson A , Renaud Y , Lobaccaro JA, Baron S , Morel L , de Joussineau C
Flavonoids differentially modulate liver X receptors activity-Structure-function relationship analysis.
Published on 01 Jun 2019 in The Journal of steroid biochemistry and molecular biology , vol. 190 - pp 173-182
Fouache A , Zabaiou N , De Joussineau C , Morel L , Silvente-Poirot S, Namsi A, Lizard G, Poirot M, Makishima M, Baron S , Lobaccaro JA, Trousson A
Individual Comparison of Cholesterol Metabolism in Normal and Tumour Areas in Radical Prostatectomy Specimens from Patients with Prostate Cancer: Results of the CHOMECAP Study.
Published on 30 Mar 2019 in European urology oncology , vol. 2 - pp 198-206
Celhay O , Bousset L , Guy L, Kemeny JL, Leoni V, Caccia C, Trousson A , Damon-Soubeyrant C, De Haze A , Sabourin L, Godfraind C, de Joussineau C , Pereira B, Morel L , Lobaccaro JM , Baron S
New Insights in Prostate Cancer Development and Tumor Therapy: Modulation of Nuclear Receptors and the Specific Role of Liver X Receptors.
Published on 28 Aug 2018 in International journal of molecular sciences , vol. 19
Bousset L , Rambur A , Fouache A , Bunay J, Morel L , Lobaccaro JA, Baron S , Trousson A , de Joussineau C
STAT3 Serine 727 Phosphorylation: A Relevant Target to Radiosensitize Human Glioblastoma.
Published on 30 Jan 2016 in Brain pathology (Zurich, Switzerland) , vol. 26 - pp 18-30
Ouédraogo ZG, Müller-Barthélémy M, Kemeny JL, Dedieu V, Biau J, Khalil T, Raoelfils LI, Granzotto A, Pereira B, Beaudoin C , Guissou IP, Berger M, Morel L , Chautard E, Verrelle P
mTOR transcriptionally and post-transcriptionally regulates Npm1 gene expression to contribute to enhanced proliferation in cells with Pten inactivation.
Published on 18 May 2016 in Cell cycle (Georgetown, Tex.) , vol. 15 - pp 1352-62
Boudra R , Lagrafeuille R, Lours-Calet C, de Joussineau C , Loubeau-Legros G, Chaveroux C, Saru JP , Baron S , Morel L , Beaudoin C
Anticancer activity of essential oils and their chemical components – a review.
Published on 19 Nov 2014 in American journal of cancer research , vol. 4 - pp 591-607
Bayala B , Bassole IH, Scifo R, Gnoula C, Morel L , Lobaccaro JM , Simpore J
Chemical composition, antioxidant, anti-inflammatory and anti-proliferative activities of essential oils of plants from Burkina Faso.
Published on 24 Mar 2014 in PloS one , vol. 9 - pp e92122
Bayala B , Bassole IH, Gnoula C, Nebie R, Yonli A, Morel L , Figueredo G, Nikiema JB, Lobaccaro JM , Simpore J
NPM1 silencing reduces tumour growth and MAPK signalling in prostate cancer cells.
Published on 05 May 2014 in PloS one , vol. 9 - pp e96293
Loubeau G, Boudra R , Maquaire S, Lours-Calet C, Beaudoin C , Verrelle P, Morel L
‘Auto-click’ functionalization for diversified copper(I) and gold(I) NHCs.
Published on 21 May 2014 in Dalton transactions (Cambridge, England : 2003) , vol. 43 - pp 6981-9
Ibrahim H, Gibard C, Hesling C , Guillot R, Morel L , Gautier A, Cisnetti F
Selective liver X receptor modulators (SLiMs): what use in human health?
Published on 04 Apr 2012 in Molecular and cellular endocrinology , vol. 351 - pp 129-41
Viennois E, Mouzat K, Dufour J , Morel L , Lobaccaro JM , Baron S
Anticancer activity of silver-N-heterocyclic carbene complexes: caspase-independent induction of apoptosis via mitochondrial apoptosis-inducing factor (AIF).
Published on 30 May 2012 in ChemMedChem , vol. 7 - pp 805-14
Eloy L, Jarrousse AS, Teyssot ML, Gautier A, Morel L , Jolivalt C, Cresteil T, Roland S
Lxrα regulates the androgen response in prostate epithelium.
Published on 30 Jul 2012 in Endocrinology , vol. 153 - pp 3211-23
Viennois E, Esposito T, Dufour J , Pommier A, Fabre S, Kemeny JL, Guy L, Morel L , Lobaccaro JM , Baron S
A platinum Chugaev carbene complex as a potent anticancer agent.
Published on 21 Jul 2011 in Chemical communications (Cambridge, England) , vol. 47 - pp 7830-2
Alves G, Morel L , El-Ghozzi M, Avignant D, Legeret B, Nauton L, Cisnetti F, Gautier A
Akt signaling pathway: a target for radiosensitizing human malignant glioma.
Published on 30 May 2010 in Neuro-oncology , vol. 12 - pp 434-43
Chautard E, Loubeau G, Tchirkov A, Chassagne J, Vermot-Desroches C, Morel L , Verrelle P
Toxicity of copper(I)-NHC complexes against human tumor cells: induction of cell cycle arrest, apoptosis, and DNA cleavage.
Published on 01 Jan 2009 in Chemistry (Weinheim an der Bergstrasse, Germany) , vol. 15 - pp 314-8
Teyssot ML, Jarrousse AS, Chevry A, De Haze A , Beaudoin C , Manin M, Nolan SP, Díez-González S, Morel L , Gautier A
[NPM: a new player in prostate cancer?].
Published on 30 Jan 2009 in Medecine sciences : M/S , vol. 25 - pp 19-21
Beaudoin C , Maquaire S, Léotoing L, Allemand J, Lours-Calet C, Veyssière G, Manin M, Morel L
Metal-NHC complexes: a survey of anti-cancer properties.
Published on 21 Sep 2009 in Dalton transactions (Cambridge, England : 2003) - pp 6894-902
Teyssot ML, Jarrousse AS, Manin M, Chevry A, Roche S, Norre F, Beaudoin C , Morel L , Boyer D, Mahiou R, Gautier A
Influence of nucleophosmin/B23 on DNA binding and transcriptional activity of the androgen receptor in prostate cancer cell.
Published on 01 May 2008 in Oncogene , vol. 27 - pp 2858-67
Léotoing L, Meunier L, Manin M, Mauduit C, Decaussin M, Verrijdt G, Claessens F, Benahmed M, Veyssière G, Morel L , Beaudoin C
