Maria Eugenia GALLEGO
Professeur des Universités
GALLEGO
Maria Eugenia
Professeur des Universités
Professeur Emérite
Resume
Maria Gallego is Emeritus Professor of Genetics and member of the reclab research group, studying the mechanisms by which cells maintain the integrity of their genomes. Her PhD at the University Autonoma of Madrid was followed by postdoctoral positions at the MRC London, Harvard Medical School Boston and the Centre de Genetic Moleculaire at Gif-sur-Yvette, working on the regulation of alternative mRNA splicing. In 1996 she started working on the molecular mechanisms of genetic recombination in plants at the University of Paris (Orsay) and moved to the University Blaise Pascal at Clermont-Ferrand in 1998 where she pursues her research into the molecular mechanisms responsible for the maintenance of genome integrity in the model plant Arabidopsis thaliana. She has participated in four european network grants (EU Framework) and two european Marie-Curie ITN doctoral networks as well as numerous public and industry funded projects in France.
Publications
DMC1 attenuates RAD51-mediated recombination in Arabidopsis.
Published on 30 Aug 2022 in PLoS genetics , vol. 18 - pp e1010322
Da Ines O , Bazile J , Gallego ME , White CI
RAD54 is essential for RAD51-mediated repair of meiotic DSB in Arabidopsis.
Published on 30 May 2021 in PLoS genetics , vol. 17 - pp e1008919
Hernandez Sanchez-Rebato M , Bouatta AM, Gallego ME , White CI , Da Ines O
Inhibition of the alternative lengthening of telomeres pathway by subtelomeric sequences in Saccharomyces cerevisiae.
Published on 30 Dec 2020 in DNA repair , vol. 96 - pp 102996
LSD1-LIKE1-Mediated H3K4me2 Demethylation Is Required for Homologous Recombination Repair.
Published on 30 Oct 2019 in Plant physiology , vol. 181 - pp 499-509
Hirakawa T, Kuwata K, Gallego ME , White CI , Nomoto M, Tada Y, Matsunaga S
RAD51 and RTEL1 compensate telomere loss in the absence of telomerase.
Published on 16 Mar 2018 in Nucleic acids research , vol. 46 - pp 2432-2445
Olivier M , Charbonnel C , Amiard S , White CI , Gallego ME
Analysis of the impact of the absence of RAD51 strand exchange activity in Arabidopsis meiosis.
Published on 10 Aug 2017 in PloS one , vol. 12 - pp e0183006
Singh G , Da Ines O , Gallego ME , White CI
The Structure-Specific Endonucleases MUS81 and SEND1 Are Essential for Telomere Stability in Arabidopsis.
Published on 30 Jan 2016 in The Plant cell , vol. 28 - pp 74-86
Olivier M , Da Ines O , Amiard S , Serra H , Goubely C , White CI , Gallego ME
Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound.
Published on 06 Nov 2015 in Scientific reports , vol. 5 - pp 16255
Merle P, Gueugneau M, Teulade-Fichou MP, Müller-Barthélémy M, Amiard S , Chautard E, Guetta C, Dedieu V, Communal Y, Mergny JL, Gallego M , White C , Verrelle P, Tchirkov A
Homology-dependent repair is involved in 45S rDNA loss in plant CAF-1 mutants.
Published on 30 Jan 2015 in The Plant journal : for cell and molecular biology , vol. 81 - pp 198-209
Muchová V, Amiard S , Mozgová I, Dvořáčková M, Gallego ME, White C , Fajkus J
Telomere stability and development of ctc1 mutants are rescued by inhibition of EJ recombination pathways in a telomerase-dependent manner.
Published on 29 Oct 2014 in Nucleic acids research , vol. 42 - pp 11979-91
Amiard S , Olivier M , Allain E , Choi K, Smith-Unna R, Henderson IR, White CI , Gallego ME
Responses to telomere erosion in plants.
Published on 01 Mar 2014 in PloS one , vol. 9 - pp e86220
Amiard S , Da Ines O , Gallego ME , White CI
Recombination-independent mechanisms and pairing of homologous chromosomes during meiosis in plants.
Published on 30 Mar 2014 in Molecular plant , vol. 7 - pp 492-501
Multiple host-cell recombination pathways act in Agrobacterium-mediated transformation of plant cells.
Published on 02 Mar 2014 in The Plant journal : for cell and molecular biology , vol. 77 - pp 511-20
Mestiri I , Norre F, Gallego ME , White CI
Roles of XRCC2, RAD51B and RAD51D in RAD51-independent SSA recombination.
Published on 30 Nov 2013 in PLoS genetics , vol. 9 - pp e1003971
Serra H , Da Ines O , Degroote F , Gallego ME , White CI
Signaling of double strand breaks and deprotected telomeres in Arabidopsis.
Published on 16 Oct 2013 in Frontiers in plant science , vol. 4 - pp 405
Meiotic recombination in Arabidopsis is catalysed by DMC1, with RAD51 playing a supporting role.
Published on 26 Sep 2013 in PLoS genetics , vol. 9 - pp e1003787
Da Ines O , Degroote F , Goubely C , Amiard S , Gallego ME , White CI
Gene targeting in maize by somatic ectopic recombination.
Published on 30 Apr 2013 in Plant biotechnology journal , vol. 11 - pp 305-14
Ayar A, Wehrkamp-Richter S, Laffaire JB, Le Goff S , Levy J, Chaignon S, Salmi H, Lepicard A, Sallaud C, Gallego ME , White CI , Paul W
Effects of XRCC2 and RAD51B mutations on somatic and meiotic recombination in Arabidopsis thaliana.
Published on 30 Jun 2013 in The Plant journal : for cell and molecular biology , vol. 74 - pp 959-70
Da Ines O , Degroote F , Amiard S , Goubely C , Gallego ME , White CI
Differing requirements for RAD51 and DMC1 in meiotic pairing of centromeres and chromosome arms in Arabidopsis thaliana.
Published on 19 Apr 2012 in PLoS genetics , vol. 8 - pp e1002636
Da Ines O , Abe K, Goubely C , Gallego ME , White CI
Arabidopsis ATM and ATR kinases prevent propagation of genome damage caused by telomere dysfunction.
Published on 30 Dec 2011 in The Plant cell , vol. 23 - pp 4254-65
Amiard S , Depeiges A , Allain E , White CI , Gallego ME
Kinetic analysis of DNA double-strand break repair pathways in Arabidopsis.
Published on 10 Jun 2011 in DNA repair , vol. 10 - pp 611-9
Recombination proteins and telomere stability in plants.
Published on 30 Mar 2011 in Current protein & peptide science , vol. 12 - pp 84-92
Distinct roles of the ATR kinase and the Mre11-Rad50-Nbs1 complex in the maintenance of chromosomal stability in Arabidopsis.
Published on 30 Sep 2010 in The Plant cell , vol. 22 - pp 3020-33
Amiard S , Charbonnel C , Allain E , Depeiges A , White CI , Gallego ME
Xrcc1-dependent and Ku-dependent DNA double-strand break repair kinetics in Arabidopsis plants.
Published on 30 Oct 2010 in The Plant journal : for cell and molecular biology , vol. 64 - pp 280-90
ERCC1/XPF protects short telomeres from homologous recombination in Arabidopsis thaliana.
Published on 02 Mar 2009 in PLoS genetics , vol. 5 - pp e1000380
Vannier JB, Depeiges A , White C , Gallego ME
Telomere-length regulation in inter-ecotype crosses of Arabidopsis.
Published on 30 Dec 2006 in Plant molecular biology , vol. 62 - pp 859-66
Maillet G, White CI , Gallego ME
Recent advances in understanding of the DNA double-strand break repair machinery of plants.
Published on 05 Jan 2006 in DNA repair , vol. 5 - pp 1-12
Bleuyard JY, Gallego ME , White CI
Two roles for Rad50 in telomere maintenance.
Published on 04 Oct 2006 in The EMBO journal , vol. 25 - pp 4577-85
Vannier JB, Depeiges A , White C , Gallego ME
DNA repair and recombination functions in Arabidopsis telomere maintenance.
Published on 01 Mar 2005 in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology , vol. 13 - pp 481-91
Differing requirements for the Arabidopsis Rad51 paralogs in meiosis and DNA repair.
Published on 02 Mar 2005 in The Plant journal : for cell and molecular biology , vol. 41 - pp 533-45
Bleuyard JY, Gallego ME , Savigny F, White CI
The atspo11-1 mutation rescues atxrcc3 meiotic chromosome fragmentation.
Published on 30 Sep 2004 in Plant molecular biology , vol. 56 - pp 217-24
Bleuyard JY, Gallego ME , White CI
Meiotic defects in the Arabidopsis rad50 mutant point to conservation of the MRX complex function in early stages of meiotic recombination.
Published on 30 Oct 2004 in Chromosoma , vol. 113 - pp 197-203
Bleuyard JY, Gallego ME , White CI
Roles of the AtErcc1 protein in recombination.
Published on 30 Aug 2004 in The Plant journal : for cell and molecular biology , vol. 39 - pp 334-42
Dubest S, Gallego ME , White CI
Telomerase dependence of telomere lengthening in Ku80 mutant Arabidopsis.
Published on 30 Mar 2003 in The Plant cell , vol. 15 - pp 782-9
Gallego ME , Jalut N, White CI
Ku80 plays a role in non-homologous recombination but is not required for T-DNA integration in Arabidopsis.
Published on 30 Sep 2003 in The Plant journal : for cell and molecular biology , vol. 35 - pp 557-65
Gallego ME , Bleuyard JY, Daoudal-Cotterell S, Jallut N, White CI
The plant Rad50-Mre11 protein complex.
Published on 10 Apr 2002 in FEBS letters , vol. 516 - pp 164-6
Daoudal-Cotterell S, Gallego ME , White CI
Role of the AtRad1p endonuclease in homologous recombination in plants.
Published on 30 Nov 2002 in EMBO reports , vol. 3 - pp 1049-54
Dubest S, Gallego ME , White CI
RAD50 function is essential for telomere maintenance in Arabidopsis.
Published on 13 Feb 2001 in Proceedings of the National Academy of Sciences of the United States of America , vol. 98 - pp 1711-6
Homologous recombination in planta is stimulated in the absence of Rad50.
Published on 30 Apr 2001 in EMBO reports , vol. 2 - pp 287-91
Gherbi H, Gallego ME , Jalut N, Lucht JM, Hohn B, White CI
Disruption of the Arabidopsis RAD50 gene leads to plant sterility and MMS sensitivity.
Published on 30 Jan 2001 in The Plant journal : for cell and molecular biology , vol. 25 - pp 31-41
Gallego ME , Jeanneau M, Granier F, Bouchez D, Bechtold N, White CI
