The NuReP group focuses its research activities on pathologies that involve lipid-sensitive nuclear receptors as well as steroid hormonal mediators. The team's goal is to improve understanding of the mechanisms linking metabolism and endocrine responses. Our attention focuses on several nuclear receptors: LXRalpha and LXRbeta, oxysterol receptors, both involved in the homeostasis of lipid metabolism, as well as AR and ER, androgen and estrogen receptors respectively, which represent master regulators of many tissues targeted by steroids. The team mainly focuses its research activity on two organs, the prostate and the ovary. In parallel, our team is developing numerous partnerships(academic, hospital, private companies, etc.) on topics of biomedical innovation concerning the pathologies that affect these two organs.