Fabrice SAEZ
Maitre de Conférences
SAEZ
Fabrice
Maitre de Conférences
MCF
Plateformes
Publications
Exploring the Epigenetic Landscape of Spermatozoa: Impact of Oxidative Stress and Antioxidant Supplementation on DNA Methylation and Hydroxymethylation.
Publié le 12 Déc 2024 dans Antioxidants (Basel, Switzerland) , vol. 13
Hug E , Renaud Y , Guiton R , Ben Sassi M, Marcaillou C, Moazamian A , Gharagozloo P, Drevet JR , Saez F
Sexual discrimination and attraction through scents in the water vole, Arvicola terrestris.
Publié le 01 Mai 2024 dans Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology , vol. 210 - pp 431-441
Poissenot K , Trouillet AC, Trives E, Moussu C, Chesneau D, Meunier M, Lattard V, Chorfa A , Saez F , Drevet J , Le Danvic C, Nagnan-Le Meillour P, Chamero P, Keller M
Loss of Nuclear/DNA Integrity in Mouse Epididymal Spermatozoa after Short-Term Exposure to Low Doses of Dibutyl Phthalate or Bisphenol AF and Its Mitigation by Oral Antioxidant Supplementation.
Publié le 05 Mai 2023 dans Antioxidants (Basel, Switzerland) , vol. 12
Hug E , Villeneuve P , Bravard S , Chorfa A , Damon-Soubeyrand C , Somkuti SG, Moazamian A , Aitken RJ, Gharagozloo P, Drevet JR , Saez F
Spermatozoa isolation with Felix™ outperforms conventional density gradient centrifugation preparation in selecting cells with low DNA damage.
Publié le 11 Jan 2023 dans Andrology
Villeneuve P , Saez F , Hug E , Chorfa A , Guiton R , Schubert B, Force A, Drevet JR
Three-dimensional imaging of vascular development in the mouse epididymis.
Publié le 13 Juin 2023 dans eLife , vol. 12
Damon-Soubeyrand C , Bongiovanni A, Chorfa A , Goubely C , Pirot N, Pardanaud L, Piboin-Fragner L, Vachias C , Bravard S , Guiton R , Thomas JL, Saez F , Kocer A , Tardivel M, Drevet JR , Henry-Berger J
When idiopathic male infertility is rooted in maternal malnutrition during the perinatal period in mice†.
Publié le 19 Mar 2022 dans Biology of reproduction , vol. 106 - pp 463-476
Muranishi Y, Parry L, Vachette-Dit-Martin M, Saez F , Coudy-Gandilhon C, Sauvanet P, Volle DH , Tournayre J, Bottari S, Carpentiero F, Martinez G, Muroňová J, Escoffier J, Bruhat A, Maurin AC, Averous J, Arnoult C, Fafournoux P, Jousse C
Field study reveals morphological and neuroendocrine correlates of seasonal breeding in female water voles, Arvicola terrestris.
Publié le 15 Sep 2021 dans General and comparative endocrinology , vol. 311 - pp 113853
Poissenot K , Moussu C, Chesneau D, Ramadier E, Abi Khalil R, Chorfa A , Chemineau P, Michelin Y, Saez F , Drevet J , Benoit E, Lattard V, Pinot A, Dardente H, Keller M
Identification of Arvicola terrestris scherman Sperm Antigens for Immune Contraceptive Purposes.
Publié le 15 Sep 2021 dans International journal of molecular sciences , vol. 22
Chorfa A , Goubely C , Henry-Berger J , Guiton R , Drevet JR , Saez F
Differential expression and localisation of TGF-β isoforms and receptors in the murine epididymis.
Publié le 22 Jan 2020 dans Scientific reports , vol. 10 - pp 995
Voisin A , Damon-Soubeyrand C , Bravard S , Saez F , Drevet JR , Guiton R
Of vessels and cells: the spatial organization of the epididymal immune system.
Publié le 01 Sep 2019 dans Andrology , vol. 7 - pp 712-718
Guiton R , Voisin A , Henry-Berger J , Saez F , Drevet JR
Impairment of sperm maturation and capacitation due to diet-dependent cholesterol overload.
Publié le 01 Sep 2019 dans Andrology , vol. 7 - pp 654-661
Dietary Cholesterol and Lipid Overload: Impact on Male Fertility.
Publié le 06 Déc 2019 dans Oxidative medicine and cellular longevity , vol. 2019 - pp 4521786
The epididymal immune balance: a key to preserving male fertility.
Publié le 01 Nov 2019 dans Asian journal of andrology , vol. 21 - pp 531-539
Slc26a3 deficiency is associated with epididymis dysplasia and impaired sperm fertilization potential in the mouse.
Publié le 01 Août 2018 dans Molecular reproduction and development , vol. 85 - pp 682-695
El Khouri E, Whitfield M , Stouvenel L, Kini A, Riederer B, Lores P, Roemermann D, di Stefano G, Drevet JR , Saez F , Seidler U, Touré A
Comprehensive overview of murine epididymal mononuclear phagocytes and lymphocytes: Unexpected populations arise.
Publié le 01 Avr 2018 dans Journal of reproductive immunology , vol. 126 - pp 11-17
Voisin A , Whitfield M , Damon-Soubeyrand C , Goubely C , Henry-Berger J , Saez F , Kocer A , Drevet JR , Guiton R
Dual extraction of mRNA and lipids from a single biological sample.
Publié le 04 Mai 2018 dans Scientific reports , vol. 8 - pp 7019
Podechard N, Ducheix S, Polizzi A, Lasserre F, Montagner A, Legagneux V, Fouché E, Saez F , Lobaccaro JM , Lakhal L, Ellero-Simatos S, Martin PG, Loiseau N, Bertrand-Michel J, Guillou H
Nuclear Integrity but Not Topology of Mouse Sperm Chromosome is Affected by Oxidative DNA Damage.
Publié le 17 Oct 2018 dans Genes , vol. 9
Champroux A , Damon-Soubeyrand C , Goubely C , Bravard S , Henry-Berger J , Guiton R , Saez F , Drevet J , Kocer A
Dyslipidemia alters sperm maturation and capacitation in LXR-null mice.
Publié le 01 Déc 2017 dans Reproduction (Cambridge, England) , vol. 154 - pp 827-842
Whitfield M , Guiton R , Rispal J , Acar N, Kocer A , Drevet JR , Saez F
Liver X Receptors (LXRs) Alpha and Beta Play Distinct Roles in the Mouse Epididymis.
Publié le 01 Mar 2016 dans Biology of reproduction , vol. 94 - pp 55
Whitfield M , Ouvrier A, Cadet R , Damon-Soubeyrand C , Guiton R , Janny L , Kocer A , Marceau G , Pons-Rejraji H , Trousson A , Drevet JR , Saez F
Posttesticular sperm maturation, infertility, and hypercholesterolemia.
Publié le 01 Sep 2015 dans Asian journal of andrology , vol. 17 - pp 742-8
Whitfield M , Pollet-Villard X, Levy R, Drevet JR , Saez F
Oxidative DNA damage in mouse sperm chromosomes: Size matters.
Publié le 01 Déc 2015 dans Free radical biology & medicine , vol. 89 - pp 993-1002
Kocer A , Henry-Berger J , Noblanc A , Champroux A , Pogorelcnik R , Guiton R , Janny L , Pons-Rejraji H , Saez F , Johnson GD, Krawetz SA, Alvarez JG, Aitken RJ, Drevet JR
Indoleamine 2,3-dioxygenase 1 (ido1) is involved in the control of mouse caput epididymis immune environment.
Publié le 20 Juin 2013 dans PloS one , vol. 8 - pp e66494
Jrad-Lamine A , Henry-Berger J , Damon-Soubeyrand C , Saez F , Kocer A , Janny L , Pons-Rejraji H , Munn DH, Mellor AL, Gharbi N, Cadet R , Guiton R , Aitken RJ, Drevet JR
DNA oxidative damage in mammalian spermatozoa: where and why is the male nucleus affected?
Publié le 01 Déc 2013 dans Free radical biology & medicine , vol. 65 - pp 719-723
Noblanc A , Damon-Soubeyrand C , Karrich B, Henry-Berger J , Cadet R , Saez F , Guiton R , Janny L , Pons-Rejraji H , Alvarez JG, Drevet JR , Kocer A
Epididymis response partly compensates for spermatozoa oxidative defects in snGPx4 and GPx5 double mutant mice.
Publié le 01 Jan 2012 dans PloS one , vol. 7 - pp e38565
Noblanc A , Peltier M, Damon-Soubeyrand C , Kerchkove N, Chabory E, Vernet P, Saez F , Cadet R , Janny L , Pons-Rejraji H , Conrad M, Drevet JR , Kocer A
Liver X receptors, lipids and their reproductive secrets in the male.
Publié le 01 Août 2011 dans Biochimica et biophysica acta , vol. 1812 - pp 974-81
El-Hajjaji FZ, Oumeddour A , Pommier AJ, Ouvrier A, Viennois E, Dufour J , Caira F , Drevet JR , Volle DH, Baron S , Saez F , Lobaccaro JM
Dietary cholesterol-induced post-testicular infertility.
Publié le 01 Jan 2011 dans PloS one , vol. 6 - pp e26966
Ouvrier A, Alves G, Damon-Soubeyrand C , Marceau G , Cadet R , Janny L , Brugnon F , Kocer A , Pommier A, Lobaccaro JM , Drevet JR , Saez F
Glutathione peroxidases at work on epididymal spermatozoa: an example of the dual effect of reactive oxygen species on mammalian male fertilizing ability.
Publié le 01 Nov 2011 dans Journal of andrology , vol. 32 - pp 641-50
Noblanc A , Kocer A , Chabory E, Vernet P, Saez F , Cadet R , Conrad M, Drevet JR
Liver X receptors, lipids and their reproductive secrets in the male.
Publié le 30 Août 2011 dans Biochimica et biophysica acta , vol. 1812 - pp 974-81
El-Hajjaji FZ, Oumeddour A , Pommier AJ, Ouvrier A, Viennois E, Dufour J , Caira F , Drevet JR, Volle DH , Baron S , Saez F , Lobaccaro JM
Epididymis cholesterol homeostasis and sperm fertilizing ability.
Publié le 30 Jan 2011 dans Asian journal of andrology , vol. 13 - pp 11-7
Deficient tryptophan catabolism along the kynurenine pathway reveals that the epididymis is in a unique tolerogenic state.
Publié le 11 Mar 2011 dans The Journal of biological chemistry , vol. 286 - pp 8030-8042
Jrad-Lamine A , Henry-Berger J , Gourbeyre P, Damon-Soubeyrand C , Lenoir A , Combaret L, Saez F , Kocer A , Tone S, Fuchs D, Zhu W, Oefner PJ, Munn DH, Mellor AL, Gharbi N, Cadet R , Aitken RJ, Drevet JR
Mammalian glutathione peroxidases control acquisition and maintenance of spermatozoa integrity.
Publié le 30 Avr 2010 dans Journal of animal science , vol. 88 - pp 1321-31
Chabory E, Damon C, Lenoir A , Henry-Berger J , Vernet P, Cadet R , Saez F , Drevet JR
LXR and ABCA1 control cholesterol homeostasis in the proximal mouse epididymis in a cell-specific manner.
Publié le 01 Sep 2009 dans Journal of lipid research , vol. 50 - pp 1766-75
Ouvrier A, Cadet R , Vernet P, Laillet B, Chardigny JM, Lobaccaro JM , Drevet JR , Saez F
LXR regulate cholesterol homeostasis in the proximal mouse epididymis.
Publié le 01 Jan 2009 dans Folia histochemica et cytobiologica , vol. 47 - pp S75-9
Ouvrier A, Cadet R , Lobaccaro JM , Drevet JR , Saez F
[Role of reactive oxygen species (ROS) on human spermatozoa and male infertility].
Publié le 30 Juin 2009 dans Gynecologie, obstetrique & fertilite , vol. 37 - pp 529-35
Pons-Rejraji H , Sion B, Saez F , Brugnon F , Janny L , Grizard G
Epididymis seleno-independent glutathione peroxidase 5 maintains sperm DNA integrity in mice.
Publié le 30 Juil 2009 dans The Journal of clinical investigation , vol. 119 - pp 2074-85
Chabory E, Damon C, Lenoir A , Kauselmann G, Kern H, Zevnik B, Garrel C, Saez F , Cadet R , Henry-Berger J , Schoor M, Gottwald U, Habenicht U, Drevet JR , Vernet P
GPX5, the selenium-independent glutathione peroxidase-encoding single copy gene is differentially expressed in mouse epididymis.
Publié le 01 Jan 2008 dans Reproduction, fertility, and development , vol. 20 - pp 615-25
Zhang T, Chabory E, Britan A, Grignard E, Pitiot O, Saez F , Cadet R , Henry-Berger J , Vernet P, Drevet JR
Protein composition of human epididymosomes collected during surgical vasectomy reversal: a proteomic and genomic approach.
Publié le 30 Août 2008 dans Human reproduction (Oxford, England) , vol. 23 - pp 1698-707
Thimon V, Frenette G, Saez F , Thabet M, Sullivan R
Liver X receptors and epididymal epithelium physiology.
Publié le 01 Juil 2007 dans Asian journal of andrology , vol. 9 - pp 574-82
Saez F , Chabory E, Cadet R , Vernet P, Baron S , Lobaccaro JM , Drevet JR
Liver X receptors and epididymal epithelium physiology.
Publié le 30 Juil 2007 dans Asian journal of andrology , vol. 9 - pp 574-82
Saez F , Chabory E, Cadet R , Vernet P, Baron S , Lobaccaro JM , Drevet JR
Identification of sperm antigens as a first step towards the generation of a contraceptive vaccine to decrease fossorial water vole Arvicola terrestris Scherman proliferations.
Publié le 15 Sep 2007 dans Theriogenology , vol. 68 - pp 779-95
Nuclear oxysterol receptors, LXRs, are involved in the maintenance of mouse caput epididymidis structure and functions.
Publié le 01 Oct 2004 dans Journal of molecular endocrinology , vol. 33 - pp 361-75
Frenoux JM, Vernet P, Volle DH, Britan A, Saez F , Kocer A , Henry-Berger J , Mangelsdorf DJ, Lobaccaro JM , Drevet JR
Nuclear oxysterol receptors, LXRs, are involved in the maintenance of mouse caput epididymidis structure and functions.
Publié le 30 Oct 2004 dans Journal of molecular endocrinology , vol. 33 - pp 361-75
Frenoux JM, Vernet P, Volle DH , Britan A, Saez F , Kocer A , Henry-Berger J , Mangelsdorf DJ, Lobaccaro JM , Drevet JR
